Complications of Diabetes Mellitus

Diabetes mellitus is one of the most widespread diseases in industrialized countries. Its macro- and microvascular complications lead to severe symptoms, mainly affecting the kidneys, the eyes, the peripheral nervous system and the heart. Since optimal blood glucose control is only achieved in a minority of patients, specific treatment options are needed which exert their effects despite hyperglycemia.

This book gives insights into pathophysiology and pathogenesis of diabetic complications. It shows a potential for pathogenetically-based therapeutic interventions which affect damaging pathways of glycolysis in

  • diabetic nephropathy
  • retinopathy
  • neuropathy and
  • diabetes-associated cardiovascular events.


Kempler, P.; Thornalley, P.J.



80 S., 56 Abb., softcover